Abnormal spontaneous brain activity in minimal hepatic encephalopathy: resting-state fMRI study

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Abnormal spontaneous brain activity in minimal hepatic encephalopathy: resting-state fMRI study.

PURPOSE We aimed to assess the abnormality of baseline spontaneous brain activity in minimal hepatic encephalopathy (MHE) by amplitude of low frequency fluctuation (ALFF) and fraction ALFF (fALFF). METHODS A total of 14 MHE patients and 14 healthy controls were included in our study. Both ALFF and fALFF of functional magnetic resonance imaging were calculated for statistical analysis. RESUL...

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Selective Impairments of Resting-State Networks in Minimal Hepatic Encephalopathy

BACKGROUND Minimal hepatic encephalopathy (MHE) is a neuro-cognitive dysfunction characterized by impairment in attention, vigilance and integrative functions, while the sensorimotor function was often unaffected. Little is known, so far, about the exact neuro-pathophysiological mechanisms of aberrant cognition function in this disease. METHODOLOGY/PRINCIPAL FINDINGS To investigate how the br...

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ژورنال

عنوان ژورنال: Diagnostic and Interventional Radiology

سال: 2016

ISSN: 1305-3825,1305-3612

DOI: 10.5152/dir.2015.15208